論文 (2006年)

  • Omori-Inoue M, Fukata H, Komiyama M, Todaka E, Osada H, Aburatani H, Mori C. The contamination levels of organochlorines and the pattern of gene expressions in human umbilical cords from intra-pairs of twins at delivery. Reprod Toxicol. 2006 Nov 12; [Epub ahead of print]
  • Uehara A, Yamamoto Y, Watanabe A, Aburatani H, Komiyama M. Construction of chimera protein by using artificial restriction DNA cutter. Nucleic Acids Symp Ser (Oxf). 2005;(49):279-80.
  • Yamamoto Y, Zhou JM, Tomita T, Uehara A, Aiba Y, Watanabe A, Aburatani H, Komiyama M. Gene manipulation using artificial restriction DNA cutter. Nucleic Acids Symp Ser (Oxf). 2005;(49):73-4.
  • Hiratsuka S, Watanabe A, Aburatani H, Maru Y. Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis. Nat Cell Biol.8(12):1369-75, 2006
  • Redon R, Ishikawa S, Fitch KR, Feuk L, Perry GH, Andrews TD, Fiegler H, Shapero MH, Carson AR, Chen W, Cho EK, Dallaire S, Freeman JL, Gonzalez JR, Gratacos M, Huang J, Kalaitzopoulos D, Komura D, Macdonald JR, Marshall CR, Mei R, Montgomery L, Nishimura K, Okamura K, Shen F, Somerville MJ, Tchinda J, Valsesia A, Woodwark C, Yang F, Zhang J, Zerjal T, Zhang J, Armengol L, Conrad DF, Estivill X, Tyler-Smith C, Carter NP, Aburatani H, Lee C, Jones KW, Scherer SW, Hurles ME. Global variation in copy number in the human genome. Nature. 444(7118):444-454. 2006
  • Komura D, Shen F, Ishikawa S, Fitch KR, Chen W, Zhang J, Liu G, Ihara S, Nakamura H, Hurles ME, Lee C, Scherer SW, Jones KW, Shapero MH, Huang J, Aburatani H. Genome-wide detection of human copy number variations using high-density DNA oligonucleotide arrays.Genome Res. 16(12):1575-1584, 2006
  • Khaja R, Zhang J, Macdonald JR, He Y, Joseph-George AM, Wei J, Rafiq MA, Qian C, Shago M, Pantano L, Aburatani H, Jones K, Redon R, Hurles M, Armengol L, Estivill X, Mural RJ, Lee C, Scherer SW, Feuk L. Genome assembly comparison identifies structural variants in the human genome. Nat Genet. 38(12):1413-8, 2006
  • Sakamoto M, Minamino T, Toko H, Kayama Y, Zou Y, Sano M, Takaki E, Aoyagi T, Tojo K, Tajima N, Nakai A, Aburatani H, Komuro I. Upregulation of Heat Shock Transcription Factor 1 Plays a Critical Role in Adaptive Cardiac Hypertrophy. Circ Res. 99(12):1411-8. 2006
  • Horiuchi K, Umetani M, Minami T, Okayama H, Takada S, Yamamoto M, Aburatani H, Reid PC, Housman DE, Hamakubo T, Kodama T. Wilms’ tumor 1-associating protein regulates G2/M transition through stabilization of cyclin A2 mRNA. Proc Natl Acad Sci U S A. 103(46):17278-83, 2006
  • Kaneshiro K, Tsutsumi S, Tsuji S, Shirahige K, Aburatani H. An Integrated Map of p53-Binding Sites and Histone Modification in the Human ENCODE Regions. Genomics 2006 Nov 2; [Epub ahead of print]
  • Takahara Y, Takahashi M, Wagatsuma H, Yokoya F, Zhang QW, Yamaguchi M, Aburatani H, Kawada N. Gene expression profiles of hepatic cell-type specific marker genes in progression of liver fibrosis. World J Gastroenterol. 12(40):6473-99. 2006
  • Hishinuma M, Ohashi KI, Yamauchi N, Kashima T, Uozaki H, Ota S, Kodama T, Aburatani H, Fukayama M. Hepatocellular oncofetal protein, glypican 3 is a sensitive marker for alpha-fetoprotein-producing gastric carcinoma. Histopathology. 49(5):479-86. 2006
  • Hayashi H, Nagae G, Tsutsumi S, Kaneshiro K, Kozaki T, Kaneda A, Sugisaki H, Aburatani H. High-resolution mapping of DNA methylation in human genome using oligonucleotide tiling array. Hum Genet. 120(5):701-11, 2007 [Sep 26, 2006; Epub ahead of print]
  • Guo Y, Chen Y, Ito H, Watanabe A, Ge X, Kodama T, Aburatani H. Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma. Gene.384:51-61, 2006. Epub 2006 Jul 28.
  • Liu H, Urabe K, Moroi Y, Yasumoto S, Kokuba H, Imafuku S, Koga T, Masuda T, Aburatani H, Furue M, Tu Y. Expression of p16 and hTERT protein is associated with the presence of high-risk human papillomavirus in Bowenoid papulosis. J Cutan Pathol. 33(8):551-8. 2006
  • Choi YL, Tsukasaki K, O’neill MC, Yamada Y, Onimaru Y, Matsumoto K, Ohashi J, Yamashita Y, Tsutsumi S, Kaneda R, Takada S, Aburatani H, Kamihira S, Nakamura T, Tomonaga M, Mano H. A genomic analysis of adult T-cell leukemia. Oncogene. 2006 Aug 14; [Epub ahead of print]
  • Ota S, Hishinuma M, Yamauchi N, Goto A, Morikawa T, Fujimura T, Kitamura T, Kodama T, Aburatani H, Fukayama M. Oncofetal protein glypican-3 in testicular germ-cell tumor. Virchows Arch. 449(3):308-14. 2006
  • Freeman JL, Perry GH, Feuk L, Redon R, McCarroll SA, Altshuler DM, Aburatani H, Jones KW, Tyler-Smith C, Hurles ME, Carter NP, Scherer SW, Lee C. Copy number variation: New insights in genome diversity. Genome Res. 16(8):949-61,2006.
  • Katou Y, Kaneshiro K, Aburatani H, Shirahige K. Genomic approach for the understanding of dynamic aspect of chromosome behavior. Methods Enzymol. 409:389-410. 2006
  • Sakaki-Yumoto M, Kobayashi C, Sato A, Fujimura S, Matsumoto Y, Takasato M, Kodama T, Aburatani H, Asashima M, Yoshida N, Nishinakamura R. The murine homolog of SALL4, a causative gene in Okihiro syndrome, is essential for embryonic stem cell proliferation, and cooperates with Sall1 in anorectal, heart, brain and kidney development. Development.133(15):3005-13. 2006
  • Komura D, Nishimura K, Ishikawa S, Panda B, Huang J, Nakamura H, Ihara S, Hirose M, Jones KW, Aburatani H. Noise Reduction from genotyping microarrays using probe level information.In Silico Biol. 11;6(1-2):0009, 2006
  • Midorikawa Y, Yamamoto S, Ishikawa S, Kamimura N, Igarashi H, Sugimura H, Makuuchi M, Aburatani H. Molecular karyotyping of human hepatocellular carcinoma using single-nucleotide polymorphism arrays. Oncogene. 2006 Jun 19; [Epub ahead of print]
  • Ito H, Funahashi S, Yamauchi N, Shibahara J, Midorikawa Y, Kawai S, Kinoshita Y, Watanabe A, Hippo Y, Ohtomo T, Iwanari H, Nakajima A, Makuuchi M, Fukayama M, Hirata Y, Hamakubo T, Kodama T, Tsuchiya M, Aburatani H. Identification of ROBO1 as a Novel Hepatocellular Carcinoma Antigen and a Potential Therapeutic and Diagnostic Target. Clin Cancer Res. 12(11):3257-64. 2006
  • Kawamura-Saito M, Yamazaki Y, Kaneko K, Kawaguchi N, Kanda H, Mukai H, Gotoh T, Motoi T, Fukayama M, Aburatani H, Takizawa T, Nakamura T. Fusion between CIC and DUX4 up-regulates PEA3 family genes in Ewing-like sarcomas with t(4;19)(q35;q13) translocation. Hum Mol Genet. 15(13):2125-37.2006.
  • Liu HJ, Moroi Y, Masuda T, Yasumoto S, Kokuba H, Imafuku S, Koga T, Tetsuya T, Tu YT, Aburatani H, Furue M, Urabe K. Expression of phosphorylated Stat3, cyclin D and Bcl-xL in extramammary Paget disease. Br J Dermatol. 154(5):926-32. 2006
  • Goto Y, Matsuzaki Y, Kurihara S, Shimizu A, Okada T, Yamamoto K, Murata H, Takata M, Aburatani H, Hoon DS, Saida T, Kawakami Y. A new melanoma antigen Fatty Acid-binding protein 7, involved in proliferation and invasion, is a potential target for immunotherapy and molecular target therapy. Cancer Res. 66(8):4443-9. 2006
  • Sheth SS, Bodnar JS, Ghazalpour A, Thipphavong CK, Tsutsumi S, Tward AD, Demant P, Kodama T, Aburatani H, Lusis AJ. Hepatocellular carcinoma in Txnip-deficient mice.Oncogene. 2006
  • Yamada T, Ishihara H, Tamura A, Takahashi R, Yamaguchi S, Takei D, Tokita A, Satake C, Tashiro F, Katagiri H, Aburatani H, Miyazaki JI, Oka Y. WFS1-deficiency increases endoplasmic reticulum stress, impairs cell cycle progression and triggers the apoptotic pathway specifically in pancreatic {beta}-cells. Hum Mol Genet. 15(10):1600-9. 2006
  • Yamada T, Katagiri H, Ishigaki Y, Ogihara T, Imai J, Uno K, Hasegawa Y, Gao J, Ishihara H, Niijima A, Mano H, Aburatani H, Asano T, Oka Y. Signals from intra-abdominal fat modulate insulin and leptin sensitivity throvugh different mechanisms: Neuronal involvement in food-intake regulation. Cell Metab. 3(3):223-9. 2006
  • Huang J, Wei W, Chen J, Zhang J, Liu G, Di X, Mei R, Ishikawa S, Aburatani H, Jones KW, Shapero MH. CARAT: A novel method for allelic detection of DNA copy number changes using high density oligonucleotide arrays. BMC Bioinformatics. 2006 Feb 21;7(1):83
  • Yamamoto Y, Uehara A, Watanabe A, Aburatani H, Komiyama M. Chemical-Reaction-Based Site-Selective DNA Cutter for PCR-Free Gene Manipulation. Chembiochem. 7(4):673-677. 2006
  • Yamashita K, Igarashi H, Kitayama Y, Ozawa T, Kiyose S, Konno H, Kazui T, Ishikawa S, Aburatani H, Tanioka F, Suzuki M, Sugimura H. Chromosomal Numerical Abnormality Profiles of Gastrointestinal Stromal Tumors. Jpn J Clin Oncol. 36(2):85-92, 2006
  • Tanaka T, Jiang S, Hotta H, Takano K, Iwanari H, Sumi K, Daigo K, Ohashi R, Sugai M, Ikegame C, Umezu H, Hirayama Y, Midorikawa Y, Hippo Y, Watanabe A, Uchiyama Y, Hasegawa G, Reid P, Aburatani H, Hamakubo T, Sakai J, Naito M, Kodama T. Dysregulated expression of P1 and P2 promoter-driven hepatocyte nuclear factor-4alpha in the pathogenesis of human cancer. J Pathol. 208(5): 662-672. 2006.
  • Chen Y, Guo Y, Ge X, Itoh H, Watanabe A, Fujiwara T, Kodama T, Aburatani H. Elevated expression and potential roles of human Sp5, a member of Sp transcription factor family, in human cancers. Biochem Biophys Res Commun. 340(3):758-66, 2006
  • Aggarwal A, Li Guo D, Hoshida Y, Tsan Yuen S, Chu KM, So S, Boussioutas A, Chen X, Bowtell D, Aburatani H, Leung SY, Tan P. Topological and functional discovery in a gene coexpression meta-network of gastric cancer. Cancer Res. 66(1):232-41. 2006
  • Nakajima H, Shibata F, Fukuchi Y, Goto-Koshino Y, Ito M, Urano A, Nakahata T, Aburatani H, Kitamura T. Immune suppressor factor confers stromal cell line with enhanced supporting activity for hematopoietic stem cells. Biochem Biophys Res Commun. 340(1):35-42. 2006
  • Sasayama T, Kato M, Aburatani H, Kuzuya A, Komiyama M. Simultaneous Genotyping of Indels and SNPs by Mass Spectroscopy. J Am Soc Mass Spectrom. 17(1):3-8. 2006
  • Takeda K, Yokoyama S, Aburatani H, Masuda T, Han F, Yoshizawa M, Yamaki N, Yamamoto H, Eguchi N, Urade Y, Shibahara S. Lipocalin-type prostaglandin D synthase as a melanocyte marker regulated by MITF. Biochem Biophys Res Commun. 339(4):1098-106. 2006
  • Okawa H, Motohashi H, Kobayashi A, Aburatani H, Kensler TW, Yamamoto M. Hepatocyte-specific deletion of the keap1 gene activates Nrf2 and confers potent resistance against acute drug toxicity. Biochem Biophys Res Commun 339(1):79-88, 2006
  • Yamazaki S, Miki K, Takayama T, Hasegawa K, Sata M, Midorikawa Y, Aburatani H, Makuuchi M. Hepatic gene induction in murine bone marrow after hepatectomy. J Hepatol. 44(2):325-333. 2006