{"id":4918,"date":"2025-07-14T10:47:46","date_gmt":"2025-07-14T01:47:46","guid":{"rendered":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/?page_id=4918"},"modified":"2025-07-14T10:47:46","modified_gmt":"2025-07-14T01:47:46","slug":"%e8%ab%96%e6%96%87-2023%e5%b9%b4","status":"publish","type":"page","link":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/en\/publications\/%e8%ab%96%e6%96%87-2023%e5%b9%b4\/","title":{"rendered":"Publication (2023)"},"content":{"rendered":"\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
\n
1.<\/div>\n<\/td>\n
\n
\n
An AsCas12f-based compact genome-editing tool derived by deep mutational scanning and structural analysis.<\/a><\/p>\n
\n
Hino T, Omura SN, Nakagawa R, Togashi T, Takeda SN, Hiramoto T, Tasaka S, Hirano H, Tokuyama T, Uosaki H, Ishiguro S, Kagieva M, Yamano H, Ozaki Y, Motooka D, Mori H, Kirita Y, Kise Y, Itoh Y, Matoba S, Aburatani H, Yachie N, Karvelis T, Siksnys V, Ohmori T, Hoshino A, Nureki O.<\/div>\n
Cell. 2023 Oct 26;186(22):4920-4935.e23. doi: 10.1016\/j.cell.2023.08.031. Epub 2023 Sep 29.<\/div>\n

PMID: 37776859<\/span><\/span><\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

\n
2.<\/div>\n<\/td>\n
\n
\n
Gut insulin action protects from hepatocarcinogenesis in diabetic mice comorbid with nonalcoholic steatohepatitis.<\/a><\/p>\n
\n
Soeda K, Sasako T, Enooku K, Kubota N, Kobayashi N, Ikushima YM, Awazawa M, Bouchi R, Toda G, Yamada T, Nakatsuka T, Tateishi R, Kakiuchi M, Yamamoto S, Tatsuno K, Atarashi K, Suda W, Honda K, Aburatani H, Yamauchi T, Fujishiro M, Noda T, Koike K, Kadowaki T, Ueki K.<\/div>\n
Nat Commun. 2023 Oct 18;14(1):6584. doi: 10.1038\/s41467-023-42334-y.<\/div>\n

PMID: 37852976<\/span><\/span> Free PMC article.<\/span><\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

\n
3.<\/div>\n<\/td>\n
\n
\n
NFIA in adipocytes reciprocally regulates mitochondrial and inflammatory gene program to improve glucose homeostasis.<\/a><\/p>\n
\n
Hiraike Y, Saito K, Oguchi M, Wada T, Toda G, Tsutsumi S, Bando K, Sagawa J, Nagano G, Ohno H, Kubota N, Kubota T, Aburatani H, Kadowaki T, Waki H, Yanagimoto S, Yamauchi T.<\/div>\n
Proc Natl Acad Sci U S A. 2023 Aug;120(31):e2308750120. doi: 10.1073\/pnas.2308750120. Epub 2023 Jul 24.<\/div>\n

PMID: 37487068<\/span><\/span> Free PMC article.<\/span><\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

\n
4.<\/div>\n<\/td>\n
\n
\n
Multiancestry genomic and transcriptomic analysis of gastric cancer.<\/a><\/p>\n
\n
Totoki Y, Saito-Adachi M, Shiraishi Y, Komura D, Nakamura H, Suzuki A, Tatsuno K, Rokutan H, Hama N, Yamamoto S, Ono H, Arai Y, Hosoda F, Katoh H, Chiba K, Iida N, Nagae G, Ueda H, Shihang C, Sekine S, Abe H, Nomura S, Matsuura T, Sakai E, Ohshima T, Rino Y, Yeoh KG, So J, Sanghvi K, Soong R, Fukagawa A, Yachida S, Kato M, Seto Y, Ushiku T, Nakajima A, Katai H, Tan P, Ishikawa S, Aburatani H, Shibata T.<\/div>\n
Nat Genet. 2023 Apr;55(4):581-594. doi: 10.1038\/s41588-023-01333-x. Epub 2023 Mar 13.<\/div>\n

PMID: 36914835<\/span><\/span><\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

\n
5.<\/div>\n<\/td>\n
\n
\n
Cross-ancestry genome-wide analysis of atrial fibrillation unveils disease biology and enables cardioembolic risk prediction.<\/a><\/p>\n
\n
Miyazawa K, Ito K, Ito M, Zou Z, Kubota M, Nomura S, Matsunaga H, Koyama S, Ieki H, Akiyama M, Koike Y, Kurosawa R, Yoshida H, Ozaki K, Onouchi Y; BioBank Japan Project; Takahashi A, Matsuda K, Murakami Y, Aburatani H, Kubo M, Momozawa Y, Terao C, Oki S, Akazawa H, Kamatani Y, Komuro I.<\/div>\n
Nat Genet. 2023 Feb;55(2):187-197. doi: 10.1038\/s41588-022-01284-9. Epub 2023 Jan 19.<\/div>\n

PMID: 36653681<\/span><\/span> Free PMC article.<\/span><\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

\n
6.<\/div>\n<\/td>\n
\n
\n
TEAD1 trapping by the Q353R-Lamin A\/C causes dilated cardiomyopathy.<\/a><\/p>\n
\n
Yamada S, Ko T, Ito M, Sassa T, Nomura S, Okuma H, Sato M, Imasaki T, Kikkawa S, Zhang B, Yamada T, Seki Y, Fujita K, Katoh M, Kubota M, Hatsuse S, Katagiri M, Hayashi H, Hamano M, Takeda N, Morita H, Takada S, Toyoda M, Uchiyama M, Ikeuchi M, Toyooka K, Umezawa A, Yamanishi Y, Nitta R, Aburatani H, Komuro I.<\/div>\n
Sci Adv. 2023 Apr 14;9(15):eade7047. doi: 10.1126\/sciadv.ade7047. Epub 2023 Apr 14.<\/div>\n

PMID: 37058558<\/span><\/span> Free PMC article.<\/span><\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

\n
7.<\/div>\n<\/td>\n
\n
\n
Convergent genomic diversity and novel BCAA metabolism in intrahepatic cholangiocarcinoma.<\/a><\/p>\n
\n
Kitagawa A, Osawa T, Noda M, Kobayashi Y, Aki S, Nakano Y, Saito T, Shimizu D, Komatsu H, Sugaya M, Takahashi J, Kosai K, Takao S, Motomura Y, Sato K, Hu Q, Fujii A, Wakiyama H, Tobo T, Uchida H, Sugimachi K, Shibata K, Utsunomiya T, Kobayashi S, Ishii H, Hasegawa T, Masuda T, Matsui Y, Niida A, Soga T, Suzuki Y, Miyano S, Aburatani H, Doki Y, Eguchi H, Mori M, Nakayama KI, Shimamura T, Shibata T, Mimori K.<\/div>\n
Br J Cancer. 2023 Jun;128(12):2206-2217. doi: 10.1038\/s41416-023-02256-4. Epub 2023 Apr 19.<\/div>\n

PMID: 37076565<\/span><\/span> Free PMC article.<\/span><\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

\n
8.<\/div>\n<\/td>\n
\n
\n
Loss of viral genome with altered immune microenvironment during tumour progression of Epstein-Barr virus-associated gastric carcinoma.<\/a><\/p>\n
\n
Kondo A, Shinozaki-Ushiku A, Rokutan H, Kunita A, Ikemura M, Yamashita H, Seto Y, Nagae G, Tatsuno K, Aburatani H, Koinuma D, Ushiku T.<\/div>\n
J Pathol. 2023 Jun;260(2):124-136. doi: 10.1002\/path.6067. Epub 2023 Mar 20.<\/div>\n

PMID: 36806225<\/span><\/span><\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

\n
9.<\/div>\n<\/td>\n
\n
\n
Clinical utility of Todai OncoPanel in the setting of approved comprehensive cancer genomic profiling tests in Japan.<\/a><\/p>\n
\n
Kage H, Shinozaki-Ushiku A, Ishigaki K, Sato Y, Tanabe M, Tanaka S, Tanikawa M, Watanabe K, Kato S, Akagi K, Uchino K, Mitani K, Takahashi S, Miura Y, Ikeda S, Kojima Y, Watanabe K, Mochizuki H, Yamaguchi H, Kawazoe Y, Kashiwabara K, Kohsaka S, Tatsuno K, Ushiku T, Ohe K, Yatomi Y, Seto Y, Aburatani H, Mano H, Miyagawa K, Oda K.<\/div>\n
Cancer Sci. 2023 Apr;114(4):1710-1717. doi: 10.1111\/cas.15717. Epub 2023 Jan 17.<\/div>\n

PMID: 36601953<\/span><\/span> Free PMC article.<\/span><\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

\n
10.<\/div>\n<\/td>\n
\n
\n
LMNA Mutations and Right Heart Failure in Patients With Cardiomyopathy and With Left Ventricular Assist Devices.<\/a><\/p>\n
\n
Yamada T, Nomura S, Amiya E, Katoh M, Inoue S, Hatsuse S, Fujita K, Ito M, Fujita T, Bujo C, Tsuji M, Ishida J, Ko T, Yamada S, Katagiri M, Sassa T, Kinoshita O, Nawata K, Tobita T, Satoh M, Ishiwata J, Daimon M, Tatsuno K, Fukuda S, Kashimura T, Minamino T, Hatano M, Ono M, Aburatani H, Komuro I.<\/div>\n
J Card Fail. 2023 May;29(5):855-857. doi: 10.1016\/j.cardfail.2023.01.011. Epub 2023 Mar 4.<\/div>\n

PMID: 36871612<\/span><\/span> No abstract available.<\/span><\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

\n
11.<\/div>\n<\/td>\n
\n
\n
Dramatic response to entrectinib in a patient with malignant peripheral nerve sheath tumor harboring novel SNRNP70-NTRK3 fusion gene.<\/a><\/p>\n
\n
Kobayashi H, Makise N, Shinozaki-Ushiku A, Zhang L, Ishibashi Y, Ikegami M, Tsuda Y, Kohsaka S, Ushiku T, Oda K, Miyagawa K, Aburatani H, Mano H, Tanaka S.<\/div>\n
Genes Chromosomes Cancer. 2023 Jan;62(1):47-51. doi: 10.1002\/gcc.23089. Epub 2022 Aug 18.<\/div>\n

PMID: 35906852<\/span><\/span><\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

\n
12.<\/div>\n<\/td>\n
\n
\n
Tumor DNA in Peritoneal Lavage as a Novel Biomarker for Predicting Peritoneal Recurrence in Patients With Gastric Cancer.<\/a><\/p>\n
\n
Yukawa N, Yamada T, Aoyama T, Woo T, Ueda K, Mastuda A, Hara K, Kazama K, Tamagawa H, Sato T, Oshima T, Suzuki A, Aburatani H, Ishikawa S, Saito A, Masuda M, Yoshida H, Rino Y.<\/div>\n
Anticancer Res. 2023 May;43(5):2069-2076. doi: 10.21873\/anticanres.16367.<\/div>\n

PMID: 37097663<\/span><\/span><\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

\n
13.<\/div>\n<\/td>\n
\n
\n
Case report and literature review: exploration of molecular therapeutic targets in recurrent malignant meningioma through comprehensive genetic analysis with Todai OncoPanel.<\/a><\/p>\n
\n
Ohara K, Miyawaki S, Nakatomi H, Okano A, Teranishi Y, Shinya Y, Ishigami D, Hongo H, Takayanagi S, Tanaka S, Shinozaki-Ushiku A, Kohsaka S, Kage H, Oda K, Miyagawa K, Aburatani H, Mano H, Tatsuno K, Saito N.<\/div>\n
Front Neurol. 2023 Nov 23;14:1270046. doi: 10.3389\/fneur.2023.1270046. eCollection 2023.<\/div>\n

PMID: 38073632<\/span><\/span> Free PMC article.<\/span><\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

1. An AsCas12f-based compact genome-editing tool derived by deep mutational scanning and structural analysis. … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":54,"featured_media":0,"parent":43,"menu_order":-2023,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-4918","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/en\/wp-json\/wp\/v2\/pages\/4918","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/en\/wp-json\/wp\/v2\/users\/54"}],"replies":[{"embeddable":true,"href":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/en\/wp-json\/wp\/v2\/comments?post=4918"}],"version-history":[{"count":3,"href":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/en\/wp-json\/wp\/v2\/pages\/4918\/revisions"}],"predecessor-version":[{"id":4921,"href":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/en\/wp-json\/wp\/v2\/pages\/4918\/revisions\/4921"}],"up":[{"embeddable":true,"href":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/en\/wp-json\/wp\/v2\/pages\/43"}],"wp:attachment":[{"href":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/en\/wp-json\/wp\/v2\/media?parent=4918"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}