{"id":4922,"date":"2025-07-14T10:53:03","date_gmt":"2025-07-14T01:53:03","guid":{"rendered":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/?page_id=4922"},"modified":"2025-07-14T10:58:45","modified_gmt":"2025-07-14T01:58:45","slug":"%e8%ab%96%e6%96%87%ef%bc%882024%e5%b9%b4%ef%bc%89","status":"publish","type":"page","link":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/en\/publications\/%e8%ab%96%e6%96%87%ef%bc%882024%e5%b9%b4%ef%bc%89\/","title":{"rendered":"Publication (2024)"},"content":{"rendered":"\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
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1.<\/div>\n<\/td>\n
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Engineering CD3\/CD137 Dual Specificity into a DLL3-Targeted T-Cell Engager Enhances T-Cell Infiltration and Efficacy against Small-Cell Lung Cancer.<\/a><\/p>\n

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Mikami H, Feng S, Matsuda Y, Ishii S, Naoi S, Azuma Y, Nagano H, Asanuma K, Kayukawa Y, Tsunenari T, Kamikawaji S, Iwabuchi R, Shinozuka J, Yamazaki M, Kuroi H, Ho SSW, Gan SW, Chichili P, Pang CL, Yeo CY, Shimizu S, Hironiwa N, Kinoshita Y, Shimizu Y, Sakamoto A, Muraoka M, Takahashi N, Kawa T, Shiraiwa H, Mimoto F, Kashima K, Kamata-Sakurai M, Ishikawa S, Aburatani H, Kitazawa T, Igawa T.<\/div>\n
Cancer Immunol Res. 2024 Jun 4;12(6):719-730. doi: 10.1158\/2326-6066.CIR-23-0638.<\/div>\n

PMID: 38558120<\/span><\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

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2.<\/div>\n<\/td>\n
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Vaccine Therapy for Heart Failure Targeting the Inflammatory Cytokine Igfbp7.<\/a><\/p>\n

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Katoh M, Nomura S, Yamada S, Ito M, Hayashi H, Katagiri M, Heryed T, Fujiwara T, Takeda N, Nishida M, Sugaya M, Kato M, Osawa T, Abe H, Sakurai Y, Ko T, Fujita K, Zhang B, Hatsuse S, Yamada T, Inoue S, Dai Z, Kubota M, Sawami K, Ono M, Morita H, Kubota Y, Mizuno S, Takahashi S, Nakanishi M, Ushiku T, Nakagami H, Aburatani H, Komuro I.<\/div>\n
Circulation. 2024 Jul 30;150(5):374-389. doi: 10.1161\/CIRCULATIONAHA.123.064719. Epub 2024 Jul 11.<\/div>\n

PMID: 38991046<\/span><\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

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3.<\/div>\n<\/td>\n
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SAIL66, a next generation CLDN6-targeting T-cell engager, demonstrates potent antitumor efficacy through dual binding to CD3\/CD137.<\/a><\/p>\n

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Kamikawa T, Kimura N, Ishii S, Muraoka M, Kodama T, Taniguchi K, Yoshimoto M, Miura-Okuda M, Uchikawa R, Kato C, Shinozuka J, Akai S, Naoi S, Tomioka N, Nagaya N, Pang CL, Garvita G, Feng S, Shimada M, Kamata-Sakurai M, Aburatani H, Kitazawa T, Igawa T.<\/div>\n
J Immunother Cancer. 2024 Oct 14;12(10):e009563. doi: 10.1136\/jitc-2024-009563.<\/div>\n

PMID: 39401967<\/span><\/span> Free PMC article.<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

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Association Between Clonal Hematopoiesis and Left Ventricular Reverse Remodeling in Nonischemic Dilated Cardiomyopathy.<\/a><\/p>\n

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Inoue S, Ko T, Shindo A, Nomura S, Yamada T, Jimba T, Dai Z, Nakao H, Suzuki A, Kashimura T, Iwahana T, Goto K, Matsushima S, Ishida J, Amiya E, Zhang B, Kubota M, Sawami K, Heryed T, Yamada S, Katoh M, Katagiri M, Ito M, Nayakama Y, Fujiu K, Hatano M, Takeda N, Takimoto E, Akazawa H, Morita H, Yamaguchi J, Inomata T, Kobayashi Y, Minamino T, Tsutsui H, Kurokawa M, Aiba A, Aburatani H, Komuro I.<\/div>\n
JACC Basic Transl Sci. 2024 Jun 12;9(8):956-967. doi: 10.1016\/j.jacbts.2024.04.010. eCollection 2024 Aug.<\/div>\n

PMID: 39297129<\/span><\/span> Free PMC article.<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

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5.<\/div>\n<\/td>\n
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Mitochondrial biogenesis in white adipose tissue mediated by JMJD1A-PGC-1 axis limits age-related metabolic disease.<\/a><\/p>\n

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Ito R, Xie S, Tumenjargal M, Sugahara Y, Yang C, Takahashi H, Arai M, Inoue SI, Uchida A, Nakano K, Choi H, Yang G, Zhao Y, Yamaguchi R, Jin H, Sagae H, Wada Y, Tanaka T, Kimura H, Kodama T, Aburatani H, Takeda K, Inagaki T, Osborne TF, Yoneshiro T, Matsumura Y, Sakai J.<\/div>\n
iScience. 2024 Mar 1;27(4):109398. doi: 10.1016\/j.isci.2024.109398. eCollection 2024 Apr 19.<\/div>\n

PMID: 38544573<\/span><\/span> Free PMC article.<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

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6.<\/div>\n<\/td>\n
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Association of Multiple Nonhypertrophic Cardiomyopathy-Related Genetic Variants and Outcomes in Patients With Hypertrophic Cardiomyopathy.<\/a><\/p>\n

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Hiruma T, Inoue S, Dai Z, Nomura S, Kubo T, Sugiura K, Suzuki A, Kashimura T, Matsushima S, Yamada T, Tobita T, Katoh M, Ko T, Ito M, Ishida J, Amiya E, Hatano M, Takeda N, Takimoto E, Akazawa H, Morita H, Yamaguchi J, Inomata T, Tsutsui H, Kitaoka H, Aburatani H, Takeda N, Komuro I.<\/div>\n
JACC Heart Fail. 2024 Dec;12(12):2041-2052. doi: 10.1016\/j.jchf.2024.08.005. Epub 2024 Sep 25.<\/div>\n

PMID: 39340495<\/span><\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

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7.<\/div>\n<\/td>\n
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Integrated genomic\/epigenomic analysis stratifies subtypes of clear cell ovarian carcinoma, highlighting their cellular origin.<\/a><\/p>\n

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Nishijima A, Oda K, Hasegawa K, Koso T, Asada K, Ikeda Y, Taguchi A, Maeda D, Nagae G, Tsuji S, Tatsuno K, Uehara Y, Kurosaki A, Sato S, Tanikawa M, Sone K, Mori M, Ikemura M, Fujiwara K, Ushiku T, Osuga Y, Aburatani H.<\/div>\n
Sci Rep. 2024 Aug 13;14(1):18797. doi: 10.1038\/s41598-024-69796-4.<\/div>\n

PMID: 39138354<\/span><\/span> Free PMC article.<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

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8.<\/div>\n<\/td>\n
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LMNA<\/em> Q353R Mutation Causes Dilated Cardiomyopathy Through Impaired Vitamin D Signaling.<\/a><\/p>\n

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Ito M, Katoh M, Sassa T, Ko T, Fujita K, Yamada S, Miura K, Toyoda M, Takada S, Tobita T, Katagiri M, Kubota M, Yamada T, Hatsuse S, Morita H, Ikeuchi M, Matsuura K, Umezawa A, Nomura S, Aburatani H, Komuro I.<\/div>\n
Circulation. 2024 Sep 17;150(12):971-974. doi: 10.1161\/CIRCULATIONAHA.124.069972. Epub 2024 Sep 16.<\/div>\n

PMID: 39283931<\/span><\/span> No abstract available.<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

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9.<\/div>\n<\/td>\n
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Transcriptomic and epigenetic dissection of spinal ependymoma (SP-EPN) identifies clinically relevant subtypes enriched for tumors with and without NF2 mutation.<\/a><\/p>\n

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Neyazi S, Yamazawa E, Hack K, Tanaka S, Nagae G, Kresbach C, Umeda T, Eckhardt A, Tatsuno K, Pohl L, Hana T, Bockmayr M, Kim P, Dorostkar MM, Takami T, Obrecht D, Takai K, Suwala AK, Komori T, Godbole S, Wefers AK, Otani R, Neumann JE, Higuchi F, Schweizer L, Nakanishi Y, Monoranu CM, Takami H, Engertsberger L, Yamada K, Ruf V, Nomura M, Mohme T, Mukasa A, Herms J, Takayanagi S, Mynarek M, Matsuura R, Lamszus K, Ishii K, Kluwe L, Imai H, von Deimling A, Koike T, Benesch M, Kushihara Y, Snuderl M, Nambu S, Frank S, Omura T, Hagel C, Kugasawa K, Mautner VF, Ichimura K, Rutkowski S, Aburatani H, Saito N, Sch\u00fcller U.<\/div>\n
Acta Neuropathol. 2024 Jan 24;147(1):22. doi: 10.1007\/s00401-023-02668-9.<\/div>\n

PMID: 38265489<\/span><\/span> Free PMC article.<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

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10.<\/div>\n<\/td>\n
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Molecular analysis of non-small cell lung cancer using a dual-targeted DNA and RNA comprehensive genomic profiling panel.<\/a><\/p>\n

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Kage H, Kohsaka S, Tatsuno K, Watanabe K, Shinozaki-Ushiku A, Isago H, Ushiku T, Aburatani H, Mano H, Oda K.<\/div>\n
Respir Investig. 2024 Sep;62(5):910-913. doi: 10.1016\/j.resinv.2024.07.018. Epub 2024 Aug 9.<\/div>\n

PMID: 39126824<\/span><\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

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11.<\/div>\n<\/td>\n
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Pooled CRISPR screening of high-content cellular phenotypes using ghost cytometry.<\/a><\/p>\n

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Tsubouchi A, An Y, Kawamura Y, Yanagihashi Y, Nakayama H, Murata Y, Teranishi K, Ishiguro S, Aburatani H, Yachie N, Ota S.<\/div>\n
Cell Rep Methods. 2024 Mar 25;4(3):100737. doi: 10.1016\/j.crmeth.2024.100737.<\/div>\n

PMID: 38531306<\/span><\/span> Free PMC article.<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

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12.<\/div>\n<\/td>\n
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Region-specific DNA hydroxymethylation along the malignant progression of IDH-mutant gliomas.<\/a><\/p>\n

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Hana T, Mukasa A, Nomura M, Nagae G, Yamamoto S, Tatsuno K, Ueda H, Fukuda S, Umeda T, Tanaka S, Nejo T, Kitagawa Y, Yamazawa E, Takahashi S, Koike T, Kushihara Y, Takami H, Takayanagi S, Aburatani H, Saito N.<\/div>\n
Cancer Sci. 2024 May;115(5):1706-1717. doi: 10.1111\/cas.16127. Epub 2024 Mar 3.<\/div>\n

PMID: 38433527<\/span><\/span> Free PMC article.<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

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13.<\/div>\n<\/td>\n
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m6ATM: a deep learning framework for demystifying the m6A epitranscriptome with Nanopore long-read RNA-seq data.<\/a><\/p>\n

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Yu B, Nagae G, Midorikawa Y, Tatsuno K, Dasgupta B, Aburatani H, Ueda H.<\/div>\n
Brief Bioinform. 2024 Sep 23;25(6):bbae529. doi: 10.1093\/bib\/bbae529.<\/div>\n

PMID: 39438075<\/span><\/span> Free PMC article.<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

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14.<\/div>\n<\/td>\n
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Analysis of quality metrics in comprehensive cancer genomic profiling using a dual DNA-RNA panel.<\/a><\/p>\n

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Watanabe K, Kohsaka S, Tatsuno K, Shinozaki-Ushiku A, Isago H, Kage H, Ushiku T, Aburatani H, Mano H, Oda K.<\/div>\n
Pract Lab Med. 2024 Feb 15;39:e00368. doi: 10.1016\/j.plabm.2024.e00368. eCollection 2024 Mar.<\/div>\n

PMID: 38404525<\/span><\/span> Free PMC article.<\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n

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15.<\/div>\n<\/td>\n
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POTENTIAL DIAGNOSTIC BIOMARKERS FOR HUMAN MESENCHYMAL TUMORS, ESPECIALLY LMP2\/\u03921I AND CYCLIN E1\/MIB1 DIFFERENTIAL EXPRESSION: PRUM-IBIO STUDY.<\/a><\/p>\n

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Tanabe Y, Hayashi T, Okada M, Aburatani H, Tonegawa S, Abiko K, Konishi I.<\/div>\n
Georgian Med News. 2024 May;(350):42-48.<\/div>\n

PMID: 39089269<\/span><\/span><\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n","protected":false},"excerpt":{"rendered":"

1. Engineering CD3\/CD137 Dual Specificity into a DLL3-Targeted T-Cell Engager Enhances T-Cell Infiltration and … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":54,"featured_media":0,"parent":43,"menu_order":-2024,"comment_status":"closed","ping_status":"closed","template":"","meta":{"footnotes":""},"class_list":["post-4922","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/en\/wp-json\/wp\/v2\/pages\/4922","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/en\/wp-json\/wp\/v2\/users\/54"}],"replies":[{"embeddable":true,"href":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/en\/wp-json\/wp\/v2\/comments?post=4922"}],"version-history":[{"count":2,"href":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/en\/wp-json\/wp\/v2\/pages\/4922\/revisions"}],"predecessor-version":[{"id":4924,"href":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/en\/wp-json\/wp\/v2\/pages\/4922\/revisions\/4924"}],"up":[{"embeddable":true,"href":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/en\/wp-json\/wp\/v2\/pages\/43"}],"wp:attachment":[{"href":"https:\/\/www.genome.rcast.u-tokyo.ac.jp\/en\/wp-json\/wp\/v2\/media?parent=4922"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}