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1.
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Engineering CD3/CD137 Dual Specificity into a DLL3-Targeted T-Cell Engager Enhances T-Cell Infiltration and Efficacy against Small-Cell Lung Cancer.
Mikami H, Feng S, Matsuda Y, Ishii S, Naoi S, Azuma Y, Nagano H, Asanuma K, Kayukawa Y, Tsunenari T, Kamikawaji S, Iwabuchi R, Shinozuka J, Yamazaki M, Kuroi H, Ho SSW, Gan SW, Chichili P, Pang CL, Yeo CY, Shimizu S, Hironiwa N, Kinoshita Y, Shimizu Y, Sakamoto A, Muraoka M, Takahashi N, Kawa T, Shiraiwa H, Mimoto F, Kashima K, Kamata-Sakurai M, Ishikawa S, Aburatani H, Kitazawa T, Igawa T.
Cancer Immunol Res. 2024 Jun 4;12(6):719-730. doi: 10.1158/2326-6066.CIR-23-0638.
PMID: 38558120
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2.
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Vaccine Therapy for Heart Failure Targeting the Inflammatory Cytokine Igfbp7.
Katoh M, Nomura S, Yamada S, Ito M, Hayashi H, Katagiri M, Heryed T, Fujiwara T, Takeda N, Nishida M, Sugaya M, Kato M, Osawa T, Abe H, Sakurai Y, Ko T, Fujita K, Zhang B, Hatsuse S, Yamada T, Inoue S, Dai Z, Kubota M, Sawami K, Ono M, Morita H, Kubota Y, Mizuno S, Takahashi S, Nakanishi M, Ushiku T, Nakagami H, Aburatani H, Komuro I.
Circulation. 2024 Jul 30;150(5):374-389. doi: 10.1161/CIRCULATIONAHA.123.064719. Epub 2024 Jul 11.
PMID: 38991046
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3.
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SAIL66, a next generation CLDN6-targeting T-cell engager, demonstrates potent antitumor efficacy through dual binding to CD3/CD137.
Kamikawa T, Kimura N, Ishii S, Muraoka M, Kodama T, Taniguchi K, Yoshimoto M, Miura-Okuda M, Uchikawa R, Kato C, Shinozuka J, Akai S, Naoi S, Tomioka N, Nagaya N, Pang CL, Garvita G, Feng S, Shimada M, Kamata-Sakurai M, Aburatani H, Kitazawa T, Igawa T.
J Immunother Cancer. 2024 Oct 14;12(10):e009563. doi: 10.1136/jitc-2024-009563.
PMID: 39401967 Free PMC article.
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4.
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Association Between Clonal Hematopoiesis and Left Ventricular Reverse Remodeling in Nonischemic Dilated Cardiomyopathy.
Inoue S, Ko T, Shindo A, Nomura S, Yamada T, Jimba T, Dai Z, Nakao H, Suzuki A, Kashimura T, Iwahana T, Goto K, Matsushima S, Ishida J, Amiya E, Zhang B, Kubota M, Sawami K, Heryed T, Yamada S, Katoh M, Katagiri M, Ito M, Nayakama Y, Fujiu K, Hatano M, Takeda N, Takimoto E, Akazawa H, Morita H, Yamaguchi J, Inomata T, Kobayashi Y, Minamino T, Tsutsui H, Kurokawa M, Aiba A, Aburatani H, Komuro I.
JACC Basic Transl Sci. 2024 Jun 12;9(8):956-967. doi: 10.1016/j.jacbts.2024.04.010. eCollection 2024 Aug.
PMID: 39297129 Free PMC article.
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5.
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Mitochondrial biogenesis in white adipose tissue mediated by JMJD1A-PGC-1 axis limits age-related metabolic disease.
Ito R, Xie S, Tumenjargal M, Sugahara Y, Yang C, Takahashi H, Arai M, Inoue SI, Uchida A, Nakano K, Choi H, Yang G, Zhao Y, Yamaguchi R, Jin H, Sagae H, Wada Y, Tanaka T, Kimura H, Kodama T, Aburatani H, Takeda K, Inagaki T, Osborne TF, Yoneshiro T, Matsumura Y, Sakai J.
iScience. 2024 Mar 1;27(4):109398. doi: 10.1016/j.isci.2024.109398. eCollection 2024 Apr 19.
PMID: 38544573 Free PMC article.
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6.
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Association of Multiple Nonhypertrophic Cardiomyopathy-Related Genetic Variants and Outcomes in Patients With Hypertrophic Cardiomyopathy.
Hiruma T, Inoue S, Dai Z, Nomura S, Kubo T, Sugiura K, Suzuki A, Kashimura T, Matsushima S, Yamada T, Tobita T, Katoh M, Ko T, Ito M, Ishida J, Amiya E, Hatano M, Takeda N, Takimoto E, Akazawa H, Morita H, Yamaguchi J, Inomata T, Tsutsui H, Kitaoka H, Aburatani H, Takeda N, Komuro I.
JACC Heart Fail. 2024 Dec;12(12):2041-2052. doi: 10.1016/j.jchf.2024.08.005. Epub 2024 Sep 25.
PMID: 39340495
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7.
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Integrated genomic/epigenomic analysis stratifies subtypes of clear cell ovarian carcinoma, highlighting their cellular origin.
Nishijima A, Oda K, Hasegawa K, Koso T, Asada K, Ikeda Y, Taguchi A, Maeda D, Nagae G, Tsuji S, Tatsuno K, Uehara Y, Kurosaki A, Sato S, Tanikawa M, Sone K, Mori M, Ikemura M, Fujiwara K, Ushiku T, Osuga Y, Aburatani H.
Sci Rep. 2024 Aug 13;14(1):18797. doi: 10.1038/s41598-024-69796-4.
PMID: 39138354 Free PMC article.
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8.
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LMNA Q353R Mutation Causes Dilated Cardiomyopathy Through Impaired Vitamin D Signaling.
Ito M, Katoh M, Sassa T, Ko T, Fujita K, Yamada S, Miura K, Toyoda M, Takada S, Tobita T, Katagiri M, Kubota M, Yamada T, Hatsuse S, Morita H, Ikeuchi M, Matsuura K, Umezawa A, Nomura S, Aburatani H, Komuro I.
Circulation. 2024 Sep 17;150(12):971-974. doi: 10.1161/CIRCULATIONAHA.124.069972. Epub 2024 Sep 16.
PMID: 39283931 No abstract available.
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9.
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Transcriptomic and epigenetic dissection of spinal ependymoma (SP-EPN) identifies clinically relevant subtypes enriched for tumors with and without NF2 mutation.
Neyazi S, Yamazawa E, Hack K, Tanaka S, Nagae G, Kresbach C, Umeda T, Eckhardt A, Tatsuno K, Pohl L, Hana T, Bockmayr M, Kim P, Dorostkar MM, Takami T, Obrecht D, Takai K, Suwala AK, Komori T, Godbole S, Wefers AK, Otani R, Neumann JE, Higuchi F, Schweizer L, Nakanishi Y, Monoranu CM, Takami H, Engertsberger L, Yamada K, Ruf V, Nomura M, Mohme T, Mukasa A, Herms J, Takayanagi S, Mynarek M, Matsuura R, Lamszus K, Ishii K, Kluwe L, Imai H, von Deimling A, Koike T, Benesch M, Kushihara Y, Snuderl M, Nambu S, Frank S, Omura T, Hagel C, Kugasawa K, Mautner VF, Ichimura K, Rutkowski S, Aburatani H, Saito N, Schüller U.
Acta Neuropathol. 2024 Jan 24;147(1):22. doi: 10.1007/s00401-023-02668-9.
PMID: 38265489 Free PMC article.
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10.
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11.
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Pooled CRISPR screening of high-content cellular phenotypes using ghost cytometry.
Tsubouchi A, An Y, Kawamura Y, Yanagihashi Y, Nakayama H, Murata Y, Teranishi K, Ishiguro S, Aburatani H, Yachie N, Ota S.
Cell Rep Methods. 2024 Mar 25;4(3):100737. doi: 10.1016/j.crmeth.2024.100737.
PMID: 38531306 Free PMC article.
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12.
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Region-specific DNA hydroxymethylation along the malignant progression of IDH-mutant gliomas.
Hana T, Mukasa A, Nomura M, Nagae G, Yamamoto S, Tatsuno K, Ueda H, Fukuda S, Umeda T, Tanaka S, Nejo T, Kitagawa Y, Yamazawa E, Takahashi S, Koike T, Kushihara Y, Takami H, Takayanagi S, Aburatani H, Saito N.
Cancer Sci. 2024 May;115(5):1706-1717. doi: 10.1111/cas.16127. Epub 2024 Mar 3.
PMID: 38433527 Free PMC article.
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