Publications (2020)

  • Shinjo K, Hara K, Nagae G, Umeda T, Katsushima K, Suzuki M, Murofushi Y, Umezu Y, Takeuchi I, Takahashi S, Okuno Y, Matsuo K, Ito H, Tajima S, Aburatani H, Yamao K, Kondo Y. A novel sensitive detection method for DNA methylation in circulating free DNA of pancreatic cancer. PLoS One. 2020 Jun 10;15(6):e0233782. doi: 10.1371/journal.pone.0233782. eCollection 2020.
  • Sakata RC, Ishiguro S, Mori H, Tanaka M, Tatsuno K, Ueda H, Yamamoto S, Seki M, Masuyama N, Nishida K, Nishimasu H, Arakawa K, Kondo A, Nureki O, Tomita M, Aburatani H, Yachie N. Base editors for simultaneous introduction of C-to-T and A-to-G mutations. Nat Biotechnol. 2020 Jun 2. doi: 10.1038/s41587-020-0509-0.
  • Matsushita H, Hasegawa K, Oda K, Yamamoto S, Asada K, Karasaki T, Yabuno A, Nishijima A, Nejo T, Kobayashi Y, Sato S, Ikeda Y, Miyai M, Takahashi Y, Yamaguchi R, Fujiwara K, Aburatani H, Kakimi K. Neoantigen load and HLA-class I expression identify a subgroup of tumors with a T-cell-inflamed phenotype and favorable prognosis in homologous recombination-proficient high-grade serous ovarian carcinoma. J Immunother Cancer. 2020 May;8(1). pii: e000375. doi: 10.1136/jitc-2019-000375.
  • Suzuki A, Katoh H, Komura D, Kakiuchi M, Tagashira A, Yamamoto S, Tatsuno K, Ueda H, Nagae G, Fukuda S, Umeda T, Totoki Y, Abe H, Ushiku T, Matsuura T, Sakai E, Ohshima T, Nomura S, Seto Y, Shibata T, Rino Y, Nakajima A, Fukayama M, Ishikawa S, Aburatani H. Defined lifestyle and germline factors predispose Asian populations to gastric cancer. Sci Adv. 2020 May 6;6(19):eaav9778. doi: 10.1126/sciadv.aav9778.
  • Sasaki Y, Asahiyama M, Tanaka T, Yamamoto S, Murakami K, Kamiya W, Matsumura Y, Osawa T, Anai M, Fruchart JC, Aburatani H, Sakai J, Kodama T. Pemafibrate, a selective PPARα modulator, prevents non-alcoholic steatohepatitis development without reducing the hepatic triglyceride content. Sci Rep. 2020 May 8;10(1):7818. doi: 10.1038/s41598-020-64902-8.
  • Sasaki K, Fukui R, Hata K, Nozawa H, Ushiku T, Aburatani H, Mano H, Ishihara S. Clinical diagnosis of a double primary sigmoid colon cancer and metastatic tumour using a gene-targeted panel test: a case report. ANZ J Surg. 2020 Apr 25. doi: 10.1111/ans.15921. [Epub ahead of print]
  • Shinozaki-Ushiku A, Ishikawa S, Komura D, Seto Y, Aburatani H, Ushiku T. The first case of gastric carcinoma with NTRK rearrangement: identification of a novel ATP1B-NTRK1 fusion. Gastric Cancer. 2020 Mar 18. doi: 10.1007/s10120-020-01061-9. [Epub ahead of print]
  • Nishiyama A, Mulholland CB, Bultmann S, Kori S, Endo A, Saeki Y, Qin W, Trummer C, Chiba Y, Yokoyama H, Kumamoto S, Kawakami T, Hojo H, Nagae G, Aburatani H, Tanaka K, Arita K, Leonhardt H, Nakanishi M. Two distinct modes of DNMT1 recruitment ensure stable maintenance DNA methylation. Nat Commun. 2020 Mar 6;11(1):1222.
  • Hayashi T, Sano K, Ichimura T, Kanai Y, Zharhary D, Aburatani H, Yaegashi N, Konishi I. Characteristics of Leiomyosarcoma: Induction of Hematogenous Metastasis by Isolated Uterine Mesenchymal Tumor Stem-like Cells. Anticancer Res. 2020 Mar;40(3):1255-1265.
  • Higashijima Y, Matsui Y, Shimamura T, Nakaki R, Nagai N, Tsutsumi S, Abe Y, Link VM, Osaka M, Yoshida M, Watanabe R, Tanaka T, Taguchi A, Miura M, Ruan X, Li G, Inoue T, Nangaku M, Kimura H, Furukawa T, Aburatani H, Wada Y, Ruan Y, Glass CK, Kanki Y. Coordinated demethylation of H3K9 and H3K27 is required for rapid inflammatory responses of endothelial cells. EMBO J. 2020 Mar 3:e103949.
  • Aizawa H, Karasaki T, Nagayama K, Shinozaki-Ushiku A, Aburatani H, Mano H, Nakajima J. Clinical Application of Next-generation Sequencing for the Diagnosis of Lung Squamous Cell Carcinoma: Is It Primary or Secondary? Intern Med. 2020 Feb 12. doi: 10.2169/internalmedicine.3682-19. [Epub ahead of print]
  • ICGC/TCGA Pan-Cancer Analysis of Whole Genomes Consortium. Pan-cancer analysis of whole genomes. 2020 Feb;578(7793):82-93.
  • Hayashi T, Sano K, Aburatani H, Yaegashi N, Konishi I. Initialization of epithelial cells by tumor cells in a metastatic microenvironment. Oncogene. 2020 Mar;39(12):2638-2640.
  • Makise N, Mori T, Kobayashi H, Nakagawa K, Ryo E, Nakajima J, Kohsaka S, Mano H, Aburatani H, Yoshida A, Ushiku T. Mesenchymal Tumors with RREB1-MRTFB Fusion Involving the Mediastinum: Extra-Glossal Ectomesenchymal Chondromyxoid Tumors? Histopathology. 2020 Jan 28. doi: 10.1111/his.14080. [Epub ahead of print]