論文 (2021年)

1.

HLA Class I Analysis Provides Insight Into the Genetic and Epigenetic Background of Immune Evasion in Colorectal Cancer With High Microsatellite Instability.

Kawazu M, Ueno T, Saeki K, Sax N, Togashi Y, Kanaseki T, Chida K, Kishigami F, Sato K, Kojima S, Otsuka M, Kawazoe A, Nishinakamura H, Yuka M, Yamamoto Y, Yamashita K, Inoue S, Tanegashima T, Matsubara D, Tane K, Tanaka Y, Iinuma H, Hashiguchi Y, Hazama S, Khor SS, Tokunaga K, Tsuboi M, Niki T, Eto M, Shitara K, Torigoe T, Ishihara S, Aburatani H, Haeno H, Nishikawa H, Mano H.
Gastroenterology. 2022 Mar;162(3):799-812. doi: 10.1053/j.gastro.2021.10.010. Epub 2021 Oct 21.

PMID: 34687740
2.

Genome-wide analysis of DNA methylation identifies the apoptosis-related gene UQCRH as a tumor suppressor in renal cancer.

Miyakuni K, Nishida J, Koinuma D, Nagae G, Aburatani H, Miyazono K, Ehata S.
Mol Oncol. 2022 Feb;16(3):732-749. doi: 10.1002/1878-0261.13040. Epub 2021 Jul 5.

PMID: 34133843 Free PMC article.
3.

Spatiotemporal dynamics of SETD5-containing NCoR-HDAC3 complex determines enhancer activation for adipogenesis.

Matsumura Y, Ito R, Yajima A, Yamaguchi R, Tanaka T, Kawamura T, Magoori K, Abe Y, Uchida A, Yoneshiro T, Hirakawa H, Zhang J, Arai M, Yang C, Yang G, Takahashi H, Fujihashi H, Nakaki R, Yamamoto S, Ota S, Tsutsumi S, Inoue SI, Kimura H, Wada Y, Kodama T, Inagaki T, Osborne TF, Aburatani H, Node K, Sakai J.
Nat Commun. 2021 Dec 2;12(1):7045. doi: 10.1038/s41467-021-27321-5.

PMID: 34857762 Free PMC article.
4.

Multi-tumor analysis of cancer-stroma interactomes of patient-derived xenografts unveils the unique homeostatic process in renal cell carcinomas.

Sueyoshi K, Komura D, Katoh H, Yamamoto A, Onoyama T, Chijiwa T, Isagawa T, Tanaka M, Suemizu H, Nakamura M, Miyagi Y, Aburatani H, Ishikawa S.
iScience. 2021 Oct 21;24(11):103322. doi: 10.1016/j.isci.2021.103322. eCollection 2021 Nov 19.

PMID: 35079698 Free PMC article.
5.

Scapular Angiomatoid Fibrous Histiocytoma with EWSR1-CREB1 Fusion in an Adult Patient.

Kobayashi H, Makise N, Shinozaki-Ushiku A, Ishibashi Y, Ikegami M, Kohsaka S, Ushiku T, Oda K, Miyagawa K, Aburatani H, Mano H, Tanaka S.
Case Rep Orthop. 2021 Sep 30;2021:9434222. doi: 10.1155/2021/9434222. eCollection 2021.

PMID: 34631187 Free PMC article.
6.

Genetic and epigenetic basis of hepatoblastoma diversity.

Nagae G, Yamamoto S, Fujita M, Fujita T, Nonaka A, Umeda T, Fukuda S, Tatsuno K, Maejima K, Hayashi A, Kurihara S, Kojima M, Hishiki T, Watanabe K, Ida K, Yano M, Hiyama Y, Tanaka Y, Inoue T, Ueda H, Nakagawa H, Aburatani H, Hiyama E.
Nat Commun. 2021 Sep 20;12(1):5423. doi: 10.1038/s41467-021-25430-9.

PMID: 34538872 Free PMC article.
7.

PITX1 inhibits the growth and proliferation of melanoma cells through regulation of SOX family genes.

Ohira T, Nakagawa S, Takeshita J, Aburatani H, Kugoh H.
Sci Rep. 2021 Sep 15;11(1):18405. doi: 10.1038/s41598-021-97791-6.

PMID: 34526609 Free PMC article.
8.

Base-resolution analysis of 5-hydroxymethylcytidine by selective oxidation and reverse transcription arrest.

Koyama K, Hayashi G, Ueda H, Ota S, Nagae G, Aburatani H, Okamoto A.
Org Biomol Chem. 2021 Jul 28;19(29):6478-6486. doi: 10.1039/d1ob00995h.

PMID: 34241617
9.

Ubiquitination-dependent and -independent repression of target genes by SETDB1 reveal a context-dependent role for its methyltransferase activity during adipogenesis.

Zhang J, Matsumura Y, Kano Y, Yoshida A, Kawamura T, Hirakawa H, Inagaki T, Tanaka T, Kimura H, Yanagi S, Fukami K, Doi T, Osborne TF, Kodama T, Aburatani H, Sakai J.
Genes Cells. 2021 Jul;26(7):513-529. doi: 10.1111/gtc.12868. Epub 2021 May 30.

PMID: 33971063
10.

TET1 upregulation drives cancer cell growth through aberrant enhancer hydroxymethylation of HMGA2 in hepatocellular carcinoma.

Shirai K, Nagae G, Seki M, Kudo Y, Kamio A, Hayashi A, Okabe A, Ota S, Tsutsumi S, Fujita T, Yamamoto S, Nakaki R, Kanki Y, Osawa T, Midorikawa Y, Tateishi K, Ichinose M, Aburatani H.
Cancer Sci. 2021 Jul;112(7):2855-2869. doi: 10.1111/cas.14897. Epub 2021 May 10.

PMID: 33970549 Free PMC article.
11.

Molecular classification and diagnostics of upper urinary tract urothelial carcinoma.

Fujii Y, Sato Y, Suzuki H, Kakiuchi N, Yoshizato T, Lenis AT, Maekawa S, Yokoyama A, Takeuchi Y, Inoue Y, Ochi Y, Shiozawa Y, Aoki K, Yoshida K, Kataoka K, Nakagawa MM, Nannya Y, Makishima H, Miyakawa J, Kawai T, Morikawa T, Shiraishi Y, Chiba K, Tanaka H, Nagae G, Sanada M, Sugihara E, Sato TA, Nakagawa T, Fukayama M, Ushiku T, Aburatani H, Miyano S, Coleman JA, Homma Y, Solit DB, Kume H, Ogawa S.
Cancer Cell. 2021 Jun 14;39(6):793-809.e8. doi: 10.1016/j.ccell.2021.05.008.

PMID: 34129823
12.

Artificial intelligence-based computational framework for drug-target prioritization and inference of novel repositionable drugs for Alzheimer’s disease.

Tsuji S, Hase T, Yachie-Kinoshita A, Nishino T, Ghosh S, Kikuchi M, Shimokawa K, Aburatani H, Kitano H, Tanaka H.
Alzheimers Res Ther. 2021 May 3;13(1):92. doi: 10.1186/s13195-021-00826-3.

PMID: 33941241 Free PMC article.
13.

Clinical practice guidance for next-generation sequencing in cancer diagnosis and treatment (edition 2.1).

Naito Y, Aburatani H, Amano T, Baba E, Furukawa T, Hayashida T, Hiyama E, Ikeda S, Kanai M, Kato M, Kinoshita I, Kiyota N, Kohno T, Kohsaka S, Komine K, Matsumura I, Miura Y, Nakamura Y, Natsume A, Nishio K, Oda K, Oda N, Okita N, Oseto K, Sunami K, Takahashi H, Takeda M, Tashiro S, Toyooka S, Ueno H, Yachida S, Yoshino T, Tsuchihara K; Japanese Society of Medical Oncology; Japan Society of Clinical Oncology; Japanese Cancer Association.
Int J Clin Oncol. 2021 Feb;26(2):233-283. doi: 10.1007/s10147-020-01831-6. Epub 2020 Nov 29.

PMID: 33249514 Free PMC article.
14.

Trib1 promotes acute myeloid leukemia progression by modulating the transcriptional programs of Hoxa9.

Yoshino S, Yokoyama T, Sunami Y, Takahara T, Nakamura A, Yamazaki Y, Tsutsumi S, Aburatani H, Nakamura T.
Blood. 2021 Jan 7;137(1):75-88. doi: 10.1182/blood.2019004586.

PMID: 32730594 Free PMC article.
15.

Single-Cardiomyocyte RNA Sequencing to Dissect the Molecular Pathophysiology of the Heart.

Katoh M, Nomura S, Yamada S, Aburatani H, Komuro I.
Methods Mol Biol. 2021;2320:183-192. doi: 10.1007/978-1-0716-1484-6_18.

PMID: 34302659
16.

Loss of Down syndrome critical region-1 leads to cholesterol metabolic dysfunction that exaggerates hypercholesterolemia in ApoE-null background.

Muramatsu M, Osawa T, Miyamura Y, Nakagawa S, Tanaka T, Kodama T, Aburatani H, Sakai J, Ryeom S, Minami T.
J Biol Chem. 2021 Jan-Jun;296:100697. doi: 10.1016/j.jbc.2021.100697. Epub 2021 Apr 23.

PMID: 33895138 Free PMC article.